Invisible Things Lab - they are focused on kernel security, virtualization security and system/firmware level security who brings up certain vulnerabilities in Intel process introducing qubes which is based on virtualization concept. core concept behind the OS is based on Security by Isolation .
Architecture mentioned in the above diagram(taken from the documentation).
I couldn't test / or willing to download ;) .
!!NOTE: You can only install Qubes on a 64-bit CPU! (most recent laptops have 64-bit CPUs)
!!!NOTE: Do not try to install Qubes in a VM, e.g. VMWare.
By the way if you want to try :